Crosslinked sodium hyaluronate gel for injection
Crosslinked sodium hyaluronate gel for injection is a specially treated sodium hyaluronate product, which is mainly used in medical cosmetology and some clinical treatments.
Main ingredients: The main ingredient of this product is sodium hyaluronate, and may also include sodium chloride, disodium hydrogen phosphate, potassium dihydrogen phosphate and other excipients.
Chemical name: (1-4) -O-beta-D glucuronic acid -(1-3) -2-acetylamino-2-deoxybeta-D glucose.
Molecular formula: (C14H20NO11Na)n.
Molecular weight: The molecular weight of sodium hyaluronate is generally between 800,000 and 2.5 million, and the higher the molecular weight, the better the viscoelasticity and the better the efficacy.
Scope of application: Crosslinked sodium hyaluronate gel for injection is mainly used for mid-to-deep injection of facial dermal tissue to correct moderate to severe nasolabial wrinkles.
Note: The product is only used in medical institutions officially approved by the state by personnel with relevant professional physician qualifications, and the operator needs to undergo professional training and obtain a training certificate.
In addition, it can also be used to improve facial depression, static skin wrinkles and tissue contours, because it is safe and absorbable, easy to operate, and immediate results, becoming one of the most commonly used fillers in minimally invasive injectable cosmetic programs.
Modified sodium hyaluronate gel for injection
Modified sodium hyaluronate gel for injection, commonly referred to as hyaluronic acid filler, is an injectable material used in medical cosmetology.
Main ingredients: The product is mainly composed of modified sodium hyaluronate, which is usually 20 mg/mL in concentration, in addition to phosphate buffers, which may contain excipients such as sodium chloride, potassium dihydrogen phosphate, and disodium hydrogen phosphate.
Product properties: Hyaluronic acid is a naturally occurring polysaccharide that is present in the skin and subcutaneous tissues and has good biocompatibility. Modified sodium hyaluronate gel is a non-animal derived, sterile, transparent product with good viscoelasticity and biodegradability.
Mechanism of action: As a dermal tissue filler, it is injected into the middle layer of facial dermal tissue to repair the skin surface contour, so as to achieve cosmetic effects. The product will gradually degrade in the human body, the typical degradation time is 6-12 months after injection, and the filling effect will gradually disappear as the product degrades.
Scope of application: It is mainly used to fill the middle layer of facial dermis tissue to correct moderate and severe nasolabial wrinkles. The injection level is located in the mid-dermal layer of the facial skin and must be performed by an experienced physician under sterile conditions.
Safety: Due to the biocompatibility and degradability of sodium hyaluronate, overall safety and tolerability are high, with a low incidence of immune reactions. However, modified sodium hyaluronate gel for injection is still a Class III medical device, and it needs to strictly comply with relevant regulations and operational specifications when used.
Note: Modified sodium hyaluronate gel for injection must be used in a medical institution officially approved by the state by personnel with relevant professional physician qualifications, and the operator needs to be professionally trained and obtain a training certificate. In addition, patients with immune dysfunction, pregnant and breastfeeding women, people under 18 years of age, people with active infection at the injection site, and people who are allergic to lidocaine should avoid using this product.
External human epidermal growth factor
Exogenous epidermal growth factor (EGF) is an important bioactive molecule, widely used in medicine and cosmetology.
Molecular properties: Human epidermal growth factor is a small molecule polypeptide composed of 53 amino acids, with a molecular weight of about 6000 Dalton, with three pairs of disulfide bonds, which makes it more stable to acid, base, heat and other physical and chemical factors.
Mechanism of action: EGF activates intracellular signaling networks by binding to specific receptors on the cell membrane, promotes cell proliferation and differentiation, and thus accelerates the repair and healing of epidermal injuries.
Clinical application:
Burn wound treatment: EGF can speed up the healing rate of burn wounds and reduce the chance of scar formation. It is suitable for patients with shallow Ⅱ degree to deep Ⅱ degree skin burn.
Diabetic ulcer treatment: For diabetic ulcers, EGF can promote the healing of ulcer wounds.
Chronic ulcer wounds: including vascular and radiation ulcers, EGF helps accelerate the healing process of these chronic wounds.
Fresh and refractory skin wounds: such as ordinary wounds, foot gangrene, keratitis, perforation of eardrum, bedsore, mouth ulcer, etc., EGF has a positive therapeutic effect.
Directions: Pour lysozyme into freeze-dried powder bottle, shake well to dissolve and spray on the affected area, or follow the specific instructions of your doctor.
Safety: Topical formulations of EGF generally have a good safety profile and no serious complications have been reported. This treatment technique is relatively safe, easy to operate, and has good adaptability and application prospect.
Beauty application: EGF can also promote the metabolism of normal epidermal cells, adding to beauty skin care products can achieve whitening, anti-wrinkle, anti-aging effect. It can effectively promote the production of type I collagen and hyaluronic acid, the main substances in the dermis of adults, and help to improve skin wrinkles, sagging and other aging manifestations.